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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Sulindac
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“We recently found synergistic effects of EGCG and cancer preventive agents such as tamoxifen and sulindac , on cancer preventive activity.”
Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-alpha expression.“The … of SL … EGCG and KMP were demonstrated by a decrease in thiobaribituric acid reactive substances level, tissue nitric oxide (NO), serum, and tissue β‐catenin as … as a reduction in the multiplicity of aberrant crypt foci (ACF) with alleviation in the dysplastic changes that resulted from DMH administration.”
“Those SL combinations with KMP and EGCG have enhanced the SL activity producing greater antioxidant, anti‐inflammatory, antiproliferating, and apoptotic activities in both combinations than SL alone.”
Chemopreventive effect of sulindac in combination with epigallocatechin gallate or kaempferol against 1,2‐dimethyl hydrazine‐induced preneoplastic lesions in rats: A Comparative Study“This paper reports confirmation of the synergistic effects of EGCG with sulindac on the inhibition of intestinal tumors in multiple intestinal neoplasia (Min) mice.”
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