supp.ai
Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Sulfur
drug:
Ticrynafen
Research Papers that Mention the Interaction
“Covalent binding of TAI , as that of TA, depends on cytochrome P-450-dependent monooxygenases and is almost completely inhibited in the presence of sulfur containing nucleophiles such as glutathione, cysteine or cyteamine.”
Oxidative activation of the thiophene ring by hepatic enzymes. Hydroxylation and formation of electrophilic metabolites during metabolism of tienilic acid and its isomer by rat liver microsomes.
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