supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Sulforaphane
drug:
Methacholine
Research Papers that Mention the Interaction
“In contrast, individuals in whom sulforaphane treatment enhanced the FEV1 response to MCh , had increased expression of the activities of these genes.”
“Interestingly, in 20 % of the asthmatics, sulforaphane aggravated the bronchoconstrictor effects of MCh and in a similar number was without effect, documenting the great heterogeneity of the responsiveness of these individuals to sulforaphane.”
“Moreover, in individuals in whom the FEV1 response to MCh challenge decreased after sulforaphane administration, i.e., sulforaphane was protective, the activities of Nrf2-regulated antioxidant and anti-inflammatory genes decreased.”
“ Sulforaphane , a dietary antioxidant and antiinflammatory phytochemical derived from broccoli, may affect the pulmonary bronchoconstrictor responses to MCh and the responses to DI in asthmatic patients.”
Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways“ Sulforaphane administration significantly alleviated the OVA-induced airway hyperresponsiveness to inhaled methacholine.”
Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback