Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Sulforaphane and Aldesleukin

supplement:

Sulforaphane

Research Papers that Mention the Interaction

Administration of sulforaphane significantly enhanced the production of IL-2 and IFN-γ in metastatic tumor-bearing animals.
These data clearly suggest that sulforaphane effectively inhibited the spread of metastatic tumor cells through the stimulation of CMI, upregulation of IL-2 and IFN-γ, and downregulation of proinflammatory cytokines IL-1β, IL-6, TNF-α, and GM-CSF.
Immunopharmacology and immunotoxicology  •  2007  |  View Paper
Administration of sulforaphane significantly enhanced the production of Interleukin-2 and Interferon-γ in normal as well as tumor-bearing animals.
Immunopharmacology and immunotoxicology  •  2006  |  View Paper
Results Sulforaphane modulated the expression of the costimulatory CD80, CD83 and the suppressive B7-H1 molecules on dendritic cells and thereby promoted activation of T cells.
Frontiers in Immunology  •  2020  |  View Paper