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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Sulfaquinoxaline
supplement:
Vitamin K
Research Papers that Mention the Interaction
“When a single dose of about 50 mg of sulfaquinoxaline was administered orally with varying levels of menadione , one mole of menadione appeared to overcome the inhibitory effect of more than 800 moles of sulfaquinoxaline.”
On Inhibition of Vit. K Activity by Sulfaquinoxaline in Chicks∗ †“Both the DTT-dependent reduction of vitamin K1 epoxide and quinone, and the reduction of DCPIP by purified DT-diaphorase were inhibited by dicoumarol, warfarin, lapachol, and sulphaquinoxaline.”
Vitamin K1 2,3-epoxide and quinone reduction: mechanism and inhibition.“ Vitamin K 1 (2-methyl-3-phytyl-l, 4-naphthoquinone) was found to be 100-250 times more effective, on a weight basis, than menadione (2-methyl-l,4-naphthoquinone) in preventing the hypoprothrombinemia which results from the administration of sulfaquinoxaline.”
Hypoprothrombinemia resulting from the administration of sulfaquinoxaline.
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