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Discover Supplement-Drug Interactions

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Last Updated: 7 months ago

Possible Interaction: Sulfaquinoxaline and Vitamin K

Research Papers that Mention the Interaction

When a single dose of about 50 mg of sulfaquinoxaline was administered orally with varying levels of menadione , one mole of menadione appeared to overcome the inhibitory effect of more than 800 moles of sulfaquinoxaline.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1957  |  View Paper
Both the DTT-dependent reduction of vitamin K1 epoxide and quinone, and the reduction of DCPIP by purified DT-diaphorase were inhibited by dicoumarol, warfarin, lapachol, and sulphaquinoxaline.
Free radical research communications  •  1990  |  View Paper
Vitamin K 1 (2-methyl-3-phytyl-l, 4-naphthoquinone) was found to be 100-250 times more effective, on a weight basis, than menadione (2-methyl-l,4-naphthoquinone) in preventing the hypoprothrombinemia which results from the administration of sulfaquinoxaline.
The Journal of pharmacology and experimental therapeutics  •  1947  |  View Paper