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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Sulfamethoxazole
supplement:
Folate
Research Papers that Mention the Interaction
“The effects of these antibiotics were partially relieved by exogenous THF addition, indicating that Smx and Tmp turn off Csu assembly by inducing folate stress.”
Subinhibitory Concentrations of Trimethoprim and Sulfamethoxazole Prevent Biofilm Formation by Acinetobacter baumannii through Inhibition of Csu Pilus Expression“Both dapsone and sulfamethoxazole act inhibiting the folate biosynthetic enzyme DHPS.”
“ Sulfamethoxazole (SMX) inhibits folate biosynthesis and is active in vitro against Aspergillus spp.”
“Consistent with this result, inhibition of folate synthesis by sulfamethoxazole , a sulfonamide, led to a dose-dependent increase in C. elegans lifespan.”
Excessive folate synthesis limits lifespan in the C. elegans: E. coli aging model
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