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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Sulfadiazine and Sodium Bicarbonate

Research Papers that Mention the Interaction

sodium bicarbonate to maintain a urine pH … increase the solubility of sulphadiazine to 200 mg/100 ml, but routine alkali therapy is unnecessary if a fluid intake of at least 700 … day is given and the maximum dose of 100 mg/kg per day is not exceeded (Weinstein, 1970).
Archives of disease in childhood  •  1973  |  View Paper