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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Both nanoencapsulated quercetin and nanoencapsulated DMSA were more effective at decreasing … liver or brain compared to conventional delivery methods, but coencapsulation of quercetin … DMSA into nanoparticles had a marked synergistic effect, decreasing liver and brain arsenic levels … and 4.8μg/g to 2.2 and 1.5μg/g, respectively.”
“We conclude that coencapsulation of quercetin and DMSA may provide a more effective therapeutic strategy in the management of arsenic toxicity and also presents a novel way of combining hydrophilic and hydrophobic drugs into a single delivery system.”
Encapsulation of the flavonoid quercetin with an arsenic chelator into nanocapsules enables the simultaneous delivery of hydrophobic and hydrophilic drugs with a synergistic effect against chronic arsenic accumulation and oxidative stress.“Interestingly, combined administration of quercetin with MiADMSA had a remarkable effect in depleting total arsenic concentration from blood and soft tissues.”
“ Quercetin when co-administered with MiADMSA also provided no additional beneficial effect on blood ALAD activity but significantly brought altered platelet counts nearer to the normal value.”
Quercetin Administration During Chelation Therapy Protects Arsenic-Induced Oxidative Stress in Mice
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