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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Substance P
supplement:
Genistein
Research Papers that Mention the Interaction
“Pretreatment with genistein both inhibited tyrosine phosphorylation and abolished the priming by either substance P or TNF-alpha.”
Priming of human neutrophils by tumour necrosis factor-alpha and substance P is associated with tyrosine phosphorylation.“Voltage-clamp recordings using the perforated patch technique with simultaneous Ca2+ measurements showed that intracellular Ca2+ elevation and inward current activated by SP and BHQ were reduced by 60-70% in response to genistein.”
Calcium entry activated by store depletion in coronary endothelium is promoted by tyrosine phosphorylation.
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