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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Streptozocin
supplement:
Tryptophan
Research Papers that Mention the Interaction
“Short- and long-term STZ treatment triggered marked decreases in plasma total TRP and hypothalamus TRP levels but the diabetogenic agent diminished 5-HT metabolism in the 1-week ST-treated rats only.”
Duration of streptozotocin diabetes influences the response of hypothalamic serotonin metabolism to immobilization stress.“NAD synthesis induced by tryptophan was reduced by streptozotocin , while that induced by nicotinamide was enhanced.”
“The induction of tyrosine aminotransferase caused by tryptophan or nicotinamide was inhibited by streptozotocin.”
“ Streptozotocin-injected rats, kept on niacin-deficient diet and given a dose of L-tryptophan (intraperitoneal or oral) excreted comparatively less quantities of niacin and N1-methylnicotinamide in urine than the control nondiabetic rats.”
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