Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Streptozocin and Calcium Supplement

drug:

Streptozocin

supplement:

Calcium Supplement

Research Papers that Mention the Interaction

“ STZ caused increased intracellular calcium which could cause the initiation of endoplasmic reticulum (ER) stress.”
Streptozotocin alters glucose transport, connexin expression and endoplasmic reticulum functions in neurons and astrocytes
Neuroscience  •  2017  |  View Paper
“Hepatic plasma membrane (Ca2+ -Mg2+)-ATPase activity was markedly elevated by STZ administration.”
Streptozotocin-induced diabetes increases (Ca2+-Mg2+)-ATPase activity in hepatic plasma membranes of rats: Involvement of protein kinase C
Molecular and Cellular Biochemistry  •  2004  |  View Paper
“ STZ treatment prolonged TPS and TR90, reduced Ca2+ -induced Ca2+ release, increased resting intracellular Ca2+ levels and slowed tau associated with normal PS and +/- dL/dt.”
Transgenic overexpression of insulin-like growth factor I prevents streptozotocin-induced cardiac contractile dysfunction and beta-adrenergic response in ventricular myocytes.
The Journal of endocrinology  •  2004  |  View Paper
“Femoral-diaphyseal and -metaphyseal alkaline phosphatase activity, calcium and deoxyribonucleic acid (DNA) contents were significantly decreased by STZ administration, showing that diabetic condition causes bone loss.”
Preventive effect of zinc acexamate administration in streptozotocin-diabetic rats: Restoration of bone loss.
International journal of molecular medicine  •  2003  |  View Paper