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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“We previously demonstrated that vitamin K2 is a transcriptional regulator of bone marker genes in osteoblastic cells and that it may potentiate bone formation by activating the steroid and xenobiotic receptor, SXR.”
Steroid and Xenobiotic Receptor SXR Mediates Vitamin K2-activated Transcription of Extracellular Matrix-related Genes and Collagen Accumulation in Osteoblastic Cells*♦“Furthermore, a report of the World Health Organization (WHO) … evidence from a randomized controlled trial suggesting that vitamin K2 , which may stimulate bone formation …-carboxylation of osteocalcin and/or steroid and xenobiotic receptors (SXRs), reduces the incidence of vertebral fractures, … only modest effects on the bone mineral density (BMD).”
“These steroids block the allosteric effect of vitamin K1 on the enzyme.”
[Regulation of glucosamine synthetase activity by cholesterol and hydrocortisone].
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