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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Steroids
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“A significant difference of HSA level in the perilymph of animals with and without steroid treatment was noted (P less than .025 at 24 hours and P less than .05 at 48 hours).”
Round window membrane permeability to human serum albumin in antigen-induced otitis media.“This is the reason why the participation of HSA in the binding of steroid hormones is substantial'J; about half of the progesterone in pregnancy serum is associated with albumin (TABLE 2).”
“The results indicate that the steroids bind to HSA at site I in a pocket different from that of bilirubin.”
“The rate of proton relaxation was decreased in the presence of steroids that can be explained by a decrease of the local microviscosity of the water-protein matrix due to interaction of steroids with HSA.”
“ HSA levels in the PL significantly decreased by a steroid treatment (p<0.025 at 24 hrs and p<0.05 at 48 hrs).”
[Permeability of round window membrane to human serum albumin in chinchillas].“The affinity of the studied steroid molecules with HSA is high compared to that with AGP, and the binding constants obtained for 4A, 5A, and 6M with HSA are 5.3 ± 2 × 104, 5.3 ± 1 × 104, and 9.5 ± 0.2 × 104 M–1, respectively.”
Unraveling the Stability of Plasma Proteins upon Interaction of Synthesized Androstenedione and Its Derivatives—A Biophysical and Computational Approach
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