supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Spironolactone
supplement:
Sphingosine 1-Phosphate
Research Papers that Mention the Interaction
“ SPL regulates intracellular pools of S1P available for ligation of its five receptors and as such has a strong influence upon autocrine, paracrine and distant S1P signaling events.”
Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function.“These results suggest that intracellular S1P has a role in the PrE differentiation and that SPL may be involved in the regulation of intracellular S1P levels during this differentiation.”
Sphingosine-1-phosphate Lyase Is Involved in the Differentiation of F9 Embryonal Carcinoma Cells to Primitive Endoderm*
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback