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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Spironolactone and Digitalis

supplement:

Digitalis

Research Papers that Mention the Interaction

Also, in the Randomized Aldactone Evaluation Study, spironolactone coadministered with conventional therapy of ACE inhibitors, loop diuretics and digitalis in patients with symptomatic heart failure defined as NYHA classes III-IV, reduced total mortality by 30%.
Methods and findings in experimental and clinical pharmacology  •  2003  |  View Paper
Also, in the Randomized Aldactone Evaluation Study spironolactone coadministered with conventional therapy of ACE inhibitors, loop diuretics and digitalis in patients with symptomatic heart failure defined as NYHA classes III-IV reduces total mortality by 30%.
Journal of molecular and cellular cardiology  •  2000  |  View Paper
The inappropriate prescription, dosage and follow-up in patients treated with digitalis and spironolactone may be associated with a high rate of serious adverse events.
Italian heart journal : official journal of the Italian Federation of Cardiology  •  2004  |  View Paper