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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Spironolactone
supplement:
Digitalis
Research Papers that Mention the Interaction
“Also, in the Randomized Aldactone Evaluation Study, spironolactone coadministered with conventional therapy of ACE inhibitors, loop diuretics and digitalis in patients with symptomatic heart failure defined as NYHA classes III-IV, reduced total mortality by 30%.”
Role of intracardiac renin-angiotensin-aldosterone system in extracellular matrix remodeling.“Also, in the Randomized Aldactone Evaluation Study spironolactone coadministered with conventional therapy of ACE inhibitors, loop diuretics and digitalis in patients with symptomatic heart failure defined as NYHA classes III-IV reduces total mortality by 30%.”
“The inappropriate prescription, dosage and follow-up in patients treated with digitalis and spironolactone may be associated with a high rate of serious adverse events.”
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