“Preincubation of striatal membranes in the … of 3 mM Mn2+, Fe2+, Co2+ , EDTA, or ascorbate enhanced subsequently measured stereospecific binding of [3H]spiperone compared to control (e.g. control: Bmax = 140 fmoles/mg protein, KD = 0.21 nM; Mn2+-treated: Bmax = 253 fmoles/mg protein, KD = 0.20 nM).”