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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Sphingosine 1-Phosphate and Phosphatidylethanolamine

Research Papers that Mention the Interaction

In [14C]ethanolamine-labelled cells, S1P (0.5-5 microM) stimulated PLD-mediated hydrolysis of PtdEtn 1.5-2.1-fold.
The results indicate that S1P stimulates PLD-mediated hydrolysis of PtdEtn by a mechanism that may involve a regulatory protein kinase C isoform.
The Biochemical journal  •  1997  |  View Paper
Low (<10 mol %) concentrations of S1P also have a clear effect on the lamellar-to-inverted hexagonal transition of DEPE , i.e., they increase the transition temperature and stabilize the lamellar versus the inverted hexagonal phase.
Biophysical journal  •  2009  |  View Paper