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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Sphingosine 1-Phosphate and Ng-Nitroarginine Methyl Ester

Research Papers that Mention the Interaction

S1P increased capillary ingrowth into subcutaneously implanted Matrigel plugs in mice, and the effect of S1P was significantly reduced in mice that received NG‐nitro‐L‐arginine methyl ester (L‐NAME), an inhibitor of NOS.
Arteriosclerosis, thrombosis, and vascular biology  •  2002  |  View Paper
L-NAME also modulated S1P vasoactive responses in a tissue-specific manner.
Biology of reproduction  •  2007  |  View Paper
Furthermore, NG‐nitro‐L‐arginine methyl ester , a NO synthase inhibitor, cancelled the effect of S1P on DNA synthesis, apoptosis, and NO production in vitro as well as the protective effect of S1P on cell damage in situ.
Hepatology  •  2006  |  View Paper