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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Sphingosine 1-Phosphate and Lenalidomide

Research Papers that Mention the Interaction

Lenalidomide at 30–1000 nM significantly enhanced chemotaxis to S1P and IL‐2 generation for T cells from HIV‐negative CD4 T lymphocytopenic patients as from HIV‐infected patients, with less effect on CCL21‐elicited chemotaxis and none for IFN‐γ generation.
Clinical and experimental immunology  •  2012  |  View Paper
Lenalidomide enhanced proliferation and suppressed apoptosis of stimulated T cells from old subjects, by IL-2-dependent mechanisms, and restored diminished T cell chemotactic responses to CCL21 and sphingosine 1-phosphate.
Clinical immunology  •  2011  |  View Paper