Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Spermine and Magnesium Cation

supplement:

Magnesium Cation

Research Papers that Mention the Interaction

Low concentrations of either spermine or the shorter polyamine spermidine synergize with 5 mM magnesium ions to boost cleavage rates considerably.
Nucleic acids research  •  1998  |  View Paper
When both these blockers were present, Mg2+i apparently attenuated the inhibitory effect of spermine on the outwardly flowing IRK2 currents.
The Journal of physiology  •  1996  |  View Paper
It has been shown, that spermine (1 mM) stimulates Mg2+ , ATP-dependent Ca2+ accumulation in mitochondria irrespective of Mg2+ concentration (3 or 7 mM) in the incubation medium.
Ukrains'kyi biokhimichnyi zhurnal  •  2004  |  View Paper
Magnesium ion (2 mM) halves the concentration of spermine needed to cause DNA aggregation.
Journal of inorganic biochemistry  •  1992  |  View Paper
At a physiological concentration of Mg2+ (1 mM) and saturating Ca2+ concentration, the stimulation by 0.5 mM spermine was 4- to 5-fold, and at 0.3 mM Mg2+, the stimulation was 20- to 30-fold.
Biochemical and biophysical research communications  •  1984  |  View Paper