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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Spermine
supplement:
Levomefolate
Research Papers that Mention the Interaction
“The EC50 for spermine was determined as 8 microM and for spermidine 40 microM. The physiological concentration for spermine has been reported to be 15-19 microM. Spermine was found to increase both the Km and the V(max) with respect to methyltetrahydrofolate for the enzyme.”
Stimulation in vitro of vitamin B12-dependent methionine synthase by polyamines.
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