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Last Updated: 2 years ago

Possible Interaction: Spermine and Calcium Supplement

Research Papers that Mention the Interaction

Interestingly, calcium , known as a negative regulator of microtubule assembly, can compete with the binding of Tau and spermine with the C-terminal domain of tubulin and with the positive effect of these two partners on microtubule assembly in vitro.
The Journal of Biological Chemistry  •  2010  |  View Paper
Spermine decreased the calcium and magnesium levels in a dose-related manner; however, changes in the sodium and potassium levels could not be correlated with spermine concentration.
Archives of andrology  •  1980  |  View Paper
Direct measurement of mitochondrial [Ca] in membrane permeabilized myocytes with Fluo-4 loaded mitochondria revealed that spermine enhanced and accelerated mitochondrial Ca uptake.
American journal of physiology. Heart and circulatory physiology  •  2020  |  View Paper
Since the increase in phospholipid concentration resulted in a higher … non-dissociable protein kinase C-liposomes complex we propose that spermine , complexing to membrane binding sites both … absence and in the presence of Ca++ , could promote binding conditions that oppose to the … of the inserted form of the enzyme.
Molecular and Cellular Biochemistry  •  2005  |  View Paper
Our results indicate that divalent cations and the polyamine, spermine , are effective modulators of calcium entry into cone-dominated bipolar cells.
Advances in experimental medicine and biology  •  2002  |  View Paper
Stimulation of PA formation by spermine was enhanced by the presence of calcium.
Biochimica et biophysica acta  •  1997  |  View Paper
PS, in the presence of NMDA, glycine and spermine , produced a further increase in intracellular free calcium at concentrations of 50 and 100 microM. The prior application of CNQX, dizocilpine or both compounds together significantly attenuated this rise in free calcium.
Brain Research  •  1995  |  View Paper
At higher Ca++ concentrations, spermine does not prevent the association process but does influence the ratio between the enzyme molecules irreversibly inserted into the membrane and those reversibly associated with it.
The international journal of biochemistry & cell biology  •  1995  |  View Paper
These results demonstrate clearly that acetylspermine and spermine alike decrease intracellular calcium concentration of vascular smooth muscle, which is likely to account for the relaxation of vasculature.
The Journal of pharmacology and experimental therapeutics  •  1993  |  View Paper
They support the hypothesis that spermine increases the rate of calcium uptake by mitochondria by increasing the affinity of the uniporter for calcium.
Journal of neurochemistry  •  1987  |  View Paper
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