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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Spermine
supplement:
Alpha-Ketoglutarate
Research Papers that Mention the Interaction
“Kinetic studies at various concentrations … inhibition by magnesium and spermine was … 2‐oxoglutarate concentrations less than 0.5 mM and NADH levels less than 0.08 mM. The presence of the … accentuated the inhibitory effect of high concentrations of 2‐oxoglutarate (>2.0 mM) and NADH (>0.32 mM).”
Inhibition of Glutamate Dehydrogenase in Brain Mitochondria and Synaptosomes by Mg2+ and Polyamines: A Possible Cause for Its Low In Vivo Activity
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