Possible Interaction: Sorbitol and Vitamin C

“The results showed that both the accumulation of erythrocyte sorbitol and the S/EG ratio were strongly reduced by the addition of AA.”

“Both the accumulation of erythrocyte sorbitol and S/EG were reduced by the addition of ascorbic acid (AA) during in vitro incubations.”

“The content of erythrocyte sorbitol could be reduced by ascorbic acid (AA).”

“Others have shown that vitamin C at pharmacologic doses decreases erythrocyte (RBC) sorbitol.”

“ Ascorbic acid , or vitamin C, has been reported to lower erythrocyte sorbitol concentrations, and present studies were performed to determine the mechanism of this effect.”

“A maximal inhibition of sorbitol in the erythrocytes of 98.3% occurred when the concentration of AA was at its peak in the cells.”

“In a study with 4 subjects, 2000 mg/day AA resulted in a reduction in erythrocyte sorbitol of 56.1%.”

“The in vitro accumulation of sorbitol by human erythrocytes incubated in a physiological glucose medium was found to be strongly reduced by the addition of ascorbic acid (AA).”

“The presence of ascorbic acid caused the greatest degradation loss in methylcobalamin (70%-76%), which was minimised to 16% with added sorbitol (p < 0.05).”

“The result of the study concluded that ascorbic acid in combination with sorbitol could effectively enhance the productivity of r-hGH.”

“DURING analytical work upon certain pharmaceutical preparations of L-ascorbic … its ultra-violet absorption was repeatedly observed; namely, ascorbic acid in … D-sorbitol shows a considerable increase of its characteristic absorption peak both in neutral aqueous …) at 265 mµ and in acidic solution (pH. 2.0) at 245 mµ.”