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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Somatropin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ABSTRACT In 3 mildly osteoporotic male patients, human growth hormone administration produced increased urinary calcium and hydroxyproline excretion without reduction of fecal calcium, effects considered compatible with increased bone resorption.”
Estrogenic antagonism of metabolic effects of administered growth hormone.“Group 1 consisted of 17 subjects (CA, 12.5 +/- 2.9 years [mean +/- SD]; bone age, 9.4 +/- 2.9 years; height velocity [HV], …, 1.7 +/- 0.5 micrograms/L; and insulinlike growth factor-I, 0.49 +/- 0.27 U/mL. Group 3 consisted of 11 subjects CA, … somatropin, …).”
“In a balance study, HGH added to vitamin D appeared to increase the intestinal absorption and the retention of calcium.”
“Delayed absorption of hGH was observed with Cmax of 69.5 ± 8.…/ml and Tmax between 10 and 12 h. The administration of SR-hGH induced elevation of serum insulin-like growth factor-I (IGF-I) level … days with a maximum value higher than the predose level by ca.”
Characterization and In Vivo Study of Sustained-Release Formulation of Human Growth Hormone Using Sodium Hyaluronate“Pigs treated with rpST had higher (P < .05) Ca concentrations and total Ca in liver and kidney and higher (P < .05) Ca concentrations in muscle.”
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