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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Sodium Fluoride and Calcium Citrate

Research Papers that Mention the Interaction

Following … slow‐release sodium fluoride … calcium citrate (mean 2.4 years in 33 osteoporotic patients with no fracture during treatment), the cancellous bone velocity was significantly higher than … osteoporotic women (3082 versus 2906 m/s, p = 0.0002) and was not significantly different from that in normal postmenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research  •  1993  |  View Paper
The area under the serum concentration curve of slow‐release sodium fluoride was reduced 17‐27% by a meal or calcium citrate.
Thus, calcium citrate reduced fluoride absorption and peak fluoride concentration in serum of slow‐release sodium fluoride but did not affect the time required to reach peak concentration or the rate of subsequent decline.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research  •  1990  |  View Paper