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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Sodium Dodecyl Sulfate and Tryptophan

Research Papers that Mention the Interaction

The negative conformation-dependent CD bands at 210–225 nm of the … were more prominent than those of carboxypeptidase A. The effect of sodium dodecyl sulfate on the enzyme side chains, as expressed by the changes … bands at 286–294 nm, suggests the involvement of tryptophan residues in … interactions.
Biochimica et biophysica acta  •  1973  |  View Paper
In summary, we conclude that internal concentration of tryptophan and tyrosine makes cells more resistant to detergent such as sodium dodecyl sulfate.
Therefore, we questioned the involvement of tryptophan in the response to sodium dodecyl sulfate treatment.
PloS one  •  2019  |  View Paper
Among the peptides, Trp in position 1 becomes more motionally‐restricted in the presence of SDS , probably because this residue is located at the N‐terminal region, which presents higher conformational freedom to interact stronger with SDS molecules.
Journal of peptide science : an official publication of the European Peptide Society  •  2014  |  View Paper
An enhancement in the α-helicity of protein with increasing concentration of SDS along with exposure of tryptophans is seen.
Colloids and surfaces. B, Biointerfaces  •  2011  |  View Paper
Importantly, substitution of Phe4 with Trp increased stability in SDS treatment.
PloS one  •  2010  |  View Paper
Relative electrophoretic mobility and intrinsic fluorescence of tyrosine and tryptophan residues increased in a complex fashion as the SDS concentration was increased.
The Journal of biological chemistry  •  1990  |  View Paper
The disorganization of the native tertiary structure by SDS was expressed in a decrease of the circular dichroism bands related to the tyrosine and tryptophan chromophores and in appearance of the vibronic fine structure in the phenylalanine band zone.
Biochimica et biophysica acta  •  1978  |  View Paper
Either tryptophan or α-methyltryptophan antagonizes this effect of SDS , i.e. a higher concentration of SDS is required to produce an equivalent response in the presence of either effector substance.
The Journal of biological chemistry  •  1969  |  View Paper