Possible Interaction: Sodium Dodecyl Sulfate and Tretinoin

“The converse was also shown with a synergistic effect of RA following prior applications of SLS.”

“ Topical all-trans-retinoic acid (RA) has been reported to decrease the in vivo skin response to sodium lauryl sulfate (SLS).”

“After applying SLS , the capacitance generally decreased then returned to basal values; treatment with RA produced an overall increase.”

“Using bioengineering techniques, e.g. assessing transepidermal water loss (TEWL), capacitance and chromametry, we investigated the variations of the skin response to SLS and RA and to both chemicals applied sequentially, allowing different time periods (from 1 h to 2 weeks) between applications of SLS and RA.”

“Based on previous in vivo findings where RA reduced skin reactions to SLS,8 one would speculate that RA pretreatment may decrease SLS penetration.”

“Recent in vivo investigations have shown that pretreatment with topical all‐trans retinoic acid (RA) may diminish the skin response to sodium lauryl sulphate (SLS).”

“Thus, an increase in RA penetration was induced by SLS pretreatment; however, pretreating the skin with RA did not inhibit the percutaneous permeation of SLS.”

“Furthermore, it was found that the complexation of CD-GAMNPs … was exothermic and the presence of a surfactant sodium dodecyl sulfate ) led to the … inclusion of retinoic acid because the linear structure of sodium dodecyl sulfate made it easier … cavity of CD as compared to less linear retinoic acid.”