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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Sodium Chloride
supplement:
Taurine
Research Papers that Mention the Interaction
“Uptake of taurine into monolayer cultures of the HRPE cells was markedly stimulated by the presence of NaCl in the uptake medium whereas the uptake was negligible in its absence.”
Properties of taurine transport in a human retinal pigment epithelial cell line.“The extracellular levels of glutamate, taurine , and GABA were concentration-dependently reduced by excess NaCl ; high-affinity glutamate uptake increased.”
Hyperosmolar sodium chloride is toxic to cultured neurons and causes reduction of glucose metabolism and ATP levels, an increase in glutamate uptake, and a reduction in cytosolic calcium.“Reduction of the NaCl concentration in the perfusion medium increased the dialysate levels of NAA and taurine , but this effect was abolished when NaCl was replaced by sucrose to maintain isosmolarity.”
“These results indicate that the presence of organic osmolytes, such as sorbitol and taurine , reduces the detrimental effects of high NaCl concentration in media used for the maturation of porcine oocytes.”
“Under initial taurine equilibrium condition, a small overshoot of taurine uptake driven by an inwardly directed NaCl gradient could be observed.”
“K(+)-stimulated taurine release from both cell types was inhibited when the osmolarity was increased with sucrose or NaCl and was enhanced when the osmolarity was reduced.”
“Perfusion with media containing high concentrations of NaCl induced diminished dialysate levels of taurine , PEA, and glutamate, whereas levels of other amino acids were either unaffected or increased.”
“Glycine, proline and taurine , when present in the range 0.1–0.60 M, inhibit chromatin precipitation by sodium chloride.”
“An inwardly directed 100 mM NaCl gradient stimulated the initial rate of taurine uptake and energized a transient twofold accumulation of taurine above equilibrium ("overshoot").”
“Incremental addition of NaCl or sucrose linearly stimulates [3H]-taurine transport in an incubation of 19 h. Total taurine , measured by HPLC, increased 25% with addition of either 40 mM NaCl or 80 mM sucrose.”
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