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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Sodium Chloride
supplement:
Phosphatidylinositol 4,5-Diphosphate
Research Papers that Mention the Interaction
“Growing cells on media containing 100 mM NaCl increased their salt-tolerance but did not affect the overall phospholipid content, except that levels of phosphatidylinositol phosphate (PIP) and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] were reduced by one-third.”
Acclimation to salt modifies the activation of several osmotic stress-activated lipid signalling pathways in Chlamydomonas.“However, in response to salt stress NaCl), PIP2 levels rapidly (<30 min) increased up to 4-fold, in a time- and dose-dependent manner.”
“We then show that NaCl treatment induces dramatic increases in the levels of phosphatidylinositol 4,5-bisphosphate and diacylglycerol pyrophosphate and also affects the turnover of phosphatidylcholine.”
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