“…,VES downregulated constitutively active basal levels of phosphorylated (p)-serine-… kinase AKT (AKT) and p-mammalian target of rapamycin (mTOR), and decreased the phosphorylation of AKT substrates Bcl-2-associated death receptor and caspase-…, in addition to mTOR effectors, ribosomal protein S6 kinase β1 and eIF4E-binding protein 1.”