“…,VES downregulated constitutively active basal levels of phosphorylated (p)‑serine‑… kinase AKT (AKT) and p‑mammalian target of rapamycin (mTOR), and decreased the phosphorylation of AKT substrates Bcl‑2‑associated death receptor and caspase‑…, in addition to mTOR effectors, ribosomal protein S6 kinase β1 and eIF4E‑binding protein 1.”