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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Simvastatin
supplement:
Polypeptides
Research Papers that Mention the Interaction
“G(1)-synchronized MCF-7 cells, made quiescent by exposure to the HMG-CoA reductase inhibitor Simvastatin … medium, readily resume cell cycle progression upon stimulation with 17beta-estradiol (E(2)), even under conditions where polypeptide growth factor-triggered signal transduction pathways … by the continuous presence of Simvastatin in … medium.”
17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells.
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