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Last Updated: 3 years ago

Possible Interaction: Simvastatin and Beta Sitosterol

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drug:

Simvastatin

supplement:

Beta Sitosterol

Research Papers that Mention the Interaction

“Moreover, simvastatin pronouncedly attenuated amyloidogenesis by decreasing amyloid-β, amyloid precursor protein (APP) and beta-site APP cleaving enzyme-1.”

Simvastatin ameliorates memory impairment and neurotoxicity in streptozotocin-induced diabetic mice

Neuroscience • 2017 | View Paper

“The addition of punicalagin, or beta-sitosterol , or pomegranate juice (which contains both of the above) to simvastatin , significantly improved the statin's ability to inhibit macrophage cholesterol biosynthesis.”

[Addition of pomegranate juice to statin inhibits cholesterol accumulation in macrophages: protective role for the phytosterol beta-sitosterol and for the polyphenolic antioxidant punicalagin].

Harefuah • 2013 | View Paper

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