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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Simvastatin
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“ Adrenocorticotrophic hormone exerts marked lipid‐lowering effects in simvastatin‐treated patients.”
Adrenocorticotrophic hormone exerts marked lipid‐lowering effects in simvastatin‐treated patients“Basal levels of ACTH were higher after simvastatin (2.9 ± 1.9 pmol/1 vs 4.1 ± 2.9 pmol/l; P < 0.05) whereas basal levels of steroid hormones were not significantly changed.”
“Importantly, simvastatin treatment further diminished the adrenal glucocorticoid response to adrenocorticotropic hormone exposure (two-way ANOVA p < 0.05 for treatment).”
Simvastatin treatment aggravates the glucocorticoid insufficiency associated with hypocholesterolemia in mice.
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