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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Sevelamer
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Therapy with bisphosphonates, sevelamer and calcimimetics, as well as thyroidectomy for regulating mineral balance were anticipated to prevent calcium accumulation and inhibit VMSC apoptosis.”
Vascular progenitor cells with decalcifying potential: a step toward prevention or treatment of atherosclerotic vascular calcification?“Despite increased prevalence of DM in the sevelamer group (58%) as compared to the CBPB group (35%), CACS was significantly lower with sevelamer use (283 + or - 83 vs. 494 + or - 94, p = 0.02).”
“ Sevelamer treatment has reduced calcium concentration and increased PTH levels, resulting in the improvement of markers of bone turnover, increased bone formation and improved trabecular architecture, providing a slower progression of VC.”
“RESULTS The switch from CaCO3 to se elamer si gnificantly decreased the serum levels of cal cium, r esulting in the elevation of iPTH levels from 31+/-18 pg/mL to 95+/-96 pg/mL by 48 weeks.”
“We could decrease doses of calcium-based phosphate binders by using sevelamer hydrochloride , and that could lower the level of calcium and raise the level of intact PTH.”
“CONCLUSIONS In chronic HD patients, se elamer de creased serum total- and LDL-cholesterol as well as cal cium. ”
“In conclusion, the concomitant use of sevelamer as a phosphate binder and the dialysate of calcium concentration of 2.5 mEq/L have possibilities for worsening secondary hyperparathyroidism in patients receiving intravenous vitamin D.”
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