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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Possible Interaction: Serum Albumin, Human and Nitric Oxide-Releasing Acetylsalicylic Acid Derivative
Research Papers that Mention the Interaction
“One of them (R2-type drug, e.g., diazepam or medazepam) greatly accelerates the reaction of DA with HSA , and the other (R1-type drug, e.g., clofibric acid or octanoic acid) does not affect the reaction.”
Effects of drug bindings on the esterase-like activity of human serum albumin. VII. Subdivision of R-type drugs inhibiting the activity towards p-nitrophenyl acetate.“From the pH profiles of the kinetic parameters for the reaction of 5-nitroaspirin with HSA , the pKa value of the catalytic group constituting the reactive site towards the aspirins was estimated as about 9.5.”
“The complex formation between 5-nitroaspirin and the reactive site of HSA decreased the fluorescence intensity due to the only tryptophan residue (Trp-214) of HSA.”
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