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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Serum Albumin, Human
supplement:
Long Chain Fatty Acid
Research Papers that Mention the Interaction
“This carrier strategy for small molecule drugs is based on naturally evolved interactions between LCFAs and HSA , demonstrated here for PTX.”
“Electron paramagnetic resonance spin labeling of HSA revealed that indazolium trans-[RuCl4(1H-indazole)(NO)] and long-chain fatty acids show competitive binding to HSA.”
“Ferrocenyl-(oxoethylene)-fatty acid compounds of different fatty acid chain length probed different binding sites on HSA.”
Applications of tailored ferrocenyl molecules as electrochemical probes of biochemical interactions.“ Long-chain fatty acids regulate the binding properties of HSA in a complex manner, in which a simultaneous competitive and allosteric mechanism operates and which mainly involves domain I.”
“In a previous study, we reported that both pH- and long chain fatty acid-induced conformational changes can alter the interactive binding of ligands to the two principal binding sites of HSA , namely, site I and site II.”
Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites
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