Possible Interaction: Serum Albumin, Human and Levocetirizine

“Circular dichroism (CD) measurement showed … the secondary structure of HSA has changed in … presence of levocetirizine , and alpha-helical content decreased from 63.1% for free HSA to 54.9% for combined HSA, … accordingly the other secondary structure (beta-strand, beta-turns and others) contents increased to some extent.”

“The effect of the non-enzymatic glycosylation (NEG) on the interaction between levocetirizine and HSA signified that the administration of levocetirizine for diabetes should be different from the normal.”