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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Serum Albumin, Human
drug:
Doripenem
Research Papers that Mention the Interaction
“Drug displacement and molecular docking studies revealed that the binding site of doripenem on HSA is … on subdomain IB and III A. This study concludes that, due to significant interaction of doripenem on either subdomain … or IIIA of HSA , the availability of doripenem on … target site may be compromised.”
“Fluorescence spectroscopic study revealed considerable interaction and complex formation of doripenem and HSA as indicated by Ksv and Kq values of the order of 104 M−1 and 1012 M−1 s−1, respectively.”
“The binding of doripenem leads to alteration of the environment surrounding Trp‐214 residue of HSA as observed by UV spectroscopic study.”
Understanding the mode of binding mechanism of doripenem to human serum albumin: Spectroscopic and molecular docking approaches
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