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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Mimicking the effect of ASCT2 down-regulation, treatment of HEK-293 cells and neurons with the ASCT2 inhibitor D-threonine also increases 5-HT uptake.”
Physical and functional interactions between the serotonin transporter and the neutral amino acid transporter ASCT2.“… 5-HT resulted in (1) an uncoupling of receptor from G proteins as evidenced by a loss of high-affinity agonist binding sites and a …) a decreased ability of the receptor to inhibit cAMP accumulation, and (3) increased phosphorylation of the 5-HT1A receptor on serine and threonine residues.”
“Both phorbol esters and serotonin increase the percentage of kinase phosphorylated at threonine 613 inAplysia neurons.”
Protein Kinase C Phosphorylated at a Conserved Threonine Is Retained in the Cytoplasm*
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