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Last Updated: 2 years ago

Possible Interaction: Serotonin and Lithium Carbonate

Research Papers that Mention the Interaction

Background Previous studies suggest that brain serotonin neurotransmission may mediate the actions of lithium carbonate.
British Journal of Psychiatry  •  2000  |  View Paper
These results are consistent with the hypothesis that lithium carbonate may enhance serotonin (5-HT) receptor sensitivity, whereas TCA and second-generation antidepressants diminish 5-HT receptor sensitivity.
Archives of general psychiatry  •  1984  |  View Paper
Lithium carbonate also stabilized the output of 5-HT.
Lithium carbonate and ECTs reduced the outputs of 5-HT and 5-HIAA, respectively.
Archives of general psychiatry  •  1984  |  View Paper
Lithium carbonate treatment for 2-3 weeks produced a significant decrease in the maximum velocity (Vmax) of serotonin ( 5-HT) uptake, a measure of the number of 5-HT uptake sites in blood platelets from bipolar patients.
The possible mechanisms of the inhibitory and stimulatory effect of lithium carbonate treatment on platelet 5-HT uptake are discussed.
Journal of affective disorders  •  1983  |  View Paper
The administration of lithium carbonate for 5 days to rats increased the synthesis rate of brain serotonin , without modifying the brain level of the amine.
Psychopharmacologia  •  2004  |  View Paper
…,lithium carbonate , cesium chloride and intraventricularly administered dibutyryl cyclic AMP, as … reported to increase the rate of biosynthesis of 5-hydroxytryptamine (5-HT) in mammalian brain tissue (TOZER, NEFF and BRODIE, 1966; REID et a[., …, 1970; TAGLIAMONTE et al., 1971~; PEREZ-CRUET and EICHELMAN, 1972; TAGLIMONTE et al., 1972).
Journal of neurochemistry  •  1973  |  View Paper
ABSTRACT Background: Previous studies suggest that brain serotonin neurotransmission may mediate the actions of lithium carbonate.
Acta Neuropsychiatrica  •  2000  |  View Paper