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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Serotonin and Kaempferol

supplement:

Kaempferol

Research Papers that Mention the Interaction

Furthermore, the administration of luteolin markedly inhibited the scratching behavior and vascular permeability induced by pruritogens, such as compound 48/80 or serotonin , in ICR mice.
Molecules  •  2014  |  View Paper
Among the flavonoids examined, luteolin and quercetin significantly reduced the cellular 5-hydroxytryptamine concentration.
In conclusion, luteolin possesses a suppressive effect on extensive 5-hydroxytryptamine formation in both experimental RBL-2H3 cells and colitis models.
Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling was also suppressed by luteolin, suggesting that this pathway is one of targets of 5-hydroxytryptamine modulation by luteolin.
The ingestion of 0.1% dietary luteolin suppressed the increasing 5-hydroxytryptamine in the colorectal mucosa.
Journal of clinical biochemistry and nutrition  •  2021  |  View Paper