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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Serotonin
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“Moreover, 5-hydroxytryptamine , a treatment that induces long-term facilitation, also produced a long-term increase in Glu uptake in cultures of sensory neurons.”
Long-term regulation of neuronal high-affinity glutamate and glutamine uptake in Aplysia.“gamma-Aminobutyric acid (GABA) and glutamic acid inhibited the pumping elicited by 5-HT.”
“Adrenaline, dopamine and 5-hydroxytryptamine enhanced fast desensitizing responses of frog spinal motoneurons evoked by L-glutamic acid.”
“It remains to verify whether the type of interference observed between GLU and 5-HT is specific or can be also detected between 5-HT and other excitatory neuromediators.”
“The magnitude (in percent) of the 5-HT induced excitatory responses decreased (hyperbolic correlation, r = 0.91) when the background mean firing rate was enhanced spontaneously or by long-lasting application of GLU.”
“ L-Glutamic acid (5 x 10(-5) M) decreased [3H]serotonin release from nerve terminals of the dorsalis raphe-striatal serotonergic neurons.”
“It is concluded that the release of Glu can be modulated by 5-HT through receptors sited on Glu terminals.”
“These results suggest that L-glutamic acid and substance P may control 5-HT transmission in the basal ganglia.”
“Dopamine, noradrenaline and glutamic acid prolong the latency of the reflex, while serotonin reduces it.”
“However, the number of pushes of the door leading to the feeding through and the magnitude of the reflex are increased by catecholamines and glutamic acid , but reduced by serotonin.”
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