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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Serotonin
supplement:
Ginkgo Biloba Whole
Research Papers that Mention the Interaction
“We presently show … 1 microM 5-HT also rapidly elevates phosphorylation and activation of the mitogen-activated protein (MAP) kinases extracellular signal-regulated kinase (ERK) 1 and ERK2 of SMCs, and the enhanced phosphorylation is blocked by the antioxidants Tiron, N-acetyl-L-cysteine (NAC), and Ginkgo biloba extract.”
Serotonin stimulates mitogen-activated protein kinase activity through the formation of superoxide anion.“Further experiments revealed that GBE also blocked the release of serotonin in the peripheral blood and triggered HIF-1 induced anti-apoptotic pathways.”
“Levels of TNF-α, IL-1β and 5-HT were reduced in the hippocampus after the administration of GBE.”
Ginkgo biloba Extract Reduces Hippocampus Inflammatory Responses, Improves Cardiac Functions And Depressive Behaviors In A Heart Failure Mouse Model“In the OVX rats, GbE stimulated 5-HT microdialysate levels while it reduced hypothalamic 5-HTT protein levels.”
“ serotonin significantly reduced food intake in Sham, Sham + GbE , and OVX + GbE groups while it failed to do so in the OVX group.”
“We presently show … 1 μM 5-HT also rapidly elevates phosphorylation and activation of the mitogen-activated protein (MAP) kinases extracellular signal-regulated kinase (ERK) 1 and ERK2 of SMCs, and the enhanced phosphorylation is blocked by the antioxidants Tiron, N-acetyl-l-cysteine (NAC), and Ginkgo biloba extract.”
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