supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Serotonin Agents
supplement:
Yohimbine
Research Papers that Mention the Interaction
“Further, yohimbine decreases firing of serotonergic neurones in raphe nuclei, an action reversed by WAY100,635.”
Agonist and antagonist actions of yohimbine as compared to fluparoxan at α2‐adrenergic receptors (AR)s, serotonin (5‐HT)1A, 5‐HT1B, 5‐HT1D and dopamine D2 and D3 receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states“It potentiated the toxic effect of yohimbine , which further suggests antidepressant-like activity and facilitation of both serotonergic and noradrenergic neurotransmissions.”
Antidepressant-like property of Jobelyn®, an African unique herbal formulation, in mice.“The behavioral data further indicated that noradrenergic and serotonergic neurons as well as the benzodiazepine (BDZ) receptor may be involved in the anticonflict effect of yohimbine.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback