Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Serine and Uridine Triacetate

supplement:

Serine

Research Papers that Mention the Interaction

From these observations we estimate that the phosphorylation of Thr 231, Ser 235, and Ser 262 contributes approximately 26, approximately 9, and approximately 33%, respectively, of the overall inhibition of tau binding to microtubules.
Archives of biochemistry and biophysics  •  1998  |  View Paper
Phosphorylation of Ser and Thr residues has the potential to impact the local and global structure of Tau.
Advances in experimental medicine and biology  •  2019  |  View Paper
Phosphorylation of Tau at serine 422 promotes Tau aggregation.
Molecular and Cellular Biochemistry  •  2011  |  View Paper
CSF tau protein phosphorylated at serine 199 was increased (1.36 pM).
Journal of Neurology  •  2009  |  View Paper
Using western blot, we found that QA treatment increased the phosphorylation of tau at serine 199/202, threonine 231 and serine 396/404 in a dose dependent manner.
PloS one  •  2009  |  View Paper
Tau is phosphorylated at serine (pSer) and threonine (pThr) in NFT, and NFT morphology varies according to phosphorylated sites and tau isoform.
Psychiatry and clinical neurosciences  •  2007  |  View Paper
Recently, we demonstrated that this unique group of serines and threonines has a critical role in controlling tau toxicity in a Drosophila model of tauopathy.
Molecular biology of the cell  •  2007  |  View Paper
The phosphorylation of tau on serines and/or threonines occurs early in the disease course and altering phosphorylation has been shown to disrupt neuropathogenesis.
Front. Neurol.  •  2013  |  View Paper