Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 6 months ago

Possible Interaction: Serine and Tyrosine

supplement:

Serine

supplement:

Tyrosine

Research Papers that Mention the Interaction

Another isoform, p45 Dab1 [Dab1(271)], however, is phosphorylated by Cdk5 at one serine residue within a unique carboxyl-terminal region, and its serine phosphorylation enhances tyrosine phosphorylation by Fyn and results in progressive degradation of p45 Dab1.
Brain Research  •  2007  |  View Paper
The activation of these kinases appears to be order dependent, as it is enhanced when phosphorylation of tyrosine precedes that of serine but phosphorylation in the reverse order yields no activation.
Molecular and cellular biology  •  1994  |  View Paper
Phosphorylation on tyrosine and O-GlcNAcylation on nearby serine or threonine residues may modulate each other.
Amino Acids  •  2019  |  View Paper
When AT1 receptors are activated by angiotensin II, serine phosphorylation of insulin receptor substrate-1 (IRS-1) inhibits tyrosine phosphorylation IRS-1 induced by insulin, leading to eventual reduction of glucose uptake.
Journal of cardiovascular pharmacology  •  2013  |  View Paper
The relative levels of serine phosphorylation and tyrosine phosphorylation are negatively correlated.
Journal of Biological Chemistry  •  2004  |  View Paper
Importantly, serine 727 phosphorylation negatively modulates STAT3 tyrosine phosphorylation, which is required for dimer formation, nuclear translocation, and the DNA binding activity of this transcriptional regulator.
Molecular and cellular biology  •  1997  |  View Paper
Non‐phosphorylated threonine, tyrosine and serine are conversely ineffective.
FEBS letters  •  1993  |  View Paper
iv) Substitution of tyrosine 22 by serine lowered viral RNA packaging efficiency and yielded particles that were 400-fold less infectious; double mutant Tyr-22Thr-23----SerSer had the same infectivity as Tyr-22----Ser, whereas mutant Thr-23----Ser was fully infectious. (
Journal of virology  •  1990  |  View Paper
Inhibition of both serine and tyrosine phosphorylation was observed.
Biochemical and biophysical research communications  •  1989  |  View Paper
Tyrosine exerted a significant stimulating effect on the absorption of most amino acids absorbed from the caecum, e.g. Asp-NH2, Ser , Thr, Arg, Asp, Glu.
Acta physiologica Polonica  •  1978  |  View Paper
Show More