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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Sequence comparison and protein inhibition experiments showed that the active site (P1-P1' site) of Ajserpin was Arginine and Serine , which displayed inhibitory activity toward trypsin in a dose-dependent manner.”
Serpin-type serine protease inhibitor mediates coelomocyte apoptosis in Apostichopus japonicus.“It is heat-stable and tolerant to low pH. It inhibits the serine proteinases trypsin and chymotrypsin, but not thrombin or subtilisin.”
“Phosphorylation of Ser 5 altered the kinetics of proteolysis by two proteases, trypsin and rat plasma kallikrein, both of which cleaved between Arg 3 and Ala 4.”
Substrate phosphorylation can inhibit proteolysis by trypsin-like enzymes.
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