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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
Research Papers that Mention the Interaction
“ Sorafenib significantly reduced serine 16 phosphorylation of phospholamban (PLN, p < 0.05), while PLN threonine 17 and CaMKII (T286) phosphorylation were not altered.”
The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients“Mechanistic study revealed that sorafenib decreased phosphorylation of serine 9 (S9) of GSK3β, while increased phosphorylation of tyrosine 216 (Y216) of GSK3β.”
Sorafenib induces pigmentation via the regulation of β-catenin signaling pathway in melanoma cells.
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