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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Serine and Recombinant Interferon Beta

Research Papers that Mention the Interaction

A dose-related increase in plasma triglyceride concentration occurred during IFN-beta ser , increasing 74% for patients on low dose and 136% for patients on high doses.
IFN-beta ser affected lipoprotein lipids of patients in a dose dependent fashion.
Atherosclerosis  •  1987  |  View Paper
Northern or slot hybridization analysis of total RNA showed a 63% and 46% decrease in the steady state level of 2-5A synthetase mRNA in AD cells as compared to controls, following a 24 h and 48 h treatment with IFN-beta ser.
Biochemistry and molecular biology international  •  1994  |  View Paper
The combination of IFN-alpha and IFN-beta ser , which results in an antagonistic antiproliferative effect, also resulted in an antagonistic induction of p78.
Journal of biological response modifiers  •  1990  |  View Paper
Further analysis of one of these lines (EFC-2) in response to rIFN-alpha A demonstrated a minimum growth inhibition by day 6 of treatment, whereas a 50% inhibition of cell growth was observed with a dose of 50 U/ml of IFN-beta ser.
Journal of interferon research  •  1990  |  View Paper
Scatchard analysis of … ng/ml IFN-beta ser showed a decrease in binding affinity (control cells, Kd = 28 +/- 7 pM; IFN-beta ser-treated cells, Kd = 38 +/- 7 pM, …-gamma receptor sites (receptor number/control cell = 4257 +/- 464, receptor number/IFN-beta ser-treated cell = 5570 +/- 730; n = 2).
Cancer research  •  1990  |  View Paper
IFN-beta ser induced a greater than or equal to 50% reduction in the 7 day growth of 6 of the 15 cultures.
Anticancer research  •  1988  |  View Paper